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Colon Cancer Staging

Options updated for adjuvant colon cancer Tx.(Gastroenterology)

Mahoney, Diana

HOLLYWOOD, FLA. -- New guidelines have broadened the options for adjuvant chemotherapy in colon cancer patients who are at high risk of recurrence to include the alkylating agent oxaliplatin and the antimetabolite drug capecitabine. In the adjuvant setting, patients with stage III colon cancer (tumor-node-metastasis T1-3, N1-2 [any lymph node involvement], M0) should receive oxaliplatin with 5-fluorouracil (5-FU) and leucovorin (the FOLFOX regimen); or capecitabine (Xeloda); or 5-FU and leucovorin without oxaliplatin, Paul Engstrom, M.D., said when presenting the updated ...




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