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Effects Of Drug Addiction

Antipsychotics' effects differ in substance abusers: activation of cytochrome P-450 system by cigarette smoke appears to play a role in drug metabolism.(Addiction Psychiatry)

McNamara, Damian

SAN JUAN, P.R. -- Risperidone and ziprasidone increased adherence to inpatient substance abuse treatment for people with schizophrenia or schizoaffective disorder in a comparison that also included olanzapine and typical neuroleptic agents. Elizabeth B. Stuyt, M.D., said at the annual meeting of the American Academy of Addiction Psychiatry.

In the retrospective study, the risperidone (Risperdal) and ziprasidone (Geodon) groups experienced increased length of stay in substance abuse treatment, a higher completion rate, and greater behavioral improvements.

Cigarette smoking ...




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