Sulfa Drug List
Study Identifies Top 10 LTC Drug Interactions - NH News Notes - Long Term Care - Brief ArticleDouglas J. Edwards Making staff aware of dangerous drug interactions might be a little easier with the newly released list of America's Top Ten Particularly Dangerous Drug Interactions in Long Term Care.
The American Medical Directors Association (AMDA), in collaboration with the American Society of Consultant Pharmacists (ASCP), surveyed more than 100 physicians and pharmacists to identify common drug interactions' clinical significance and potential to cause harm, the frequency of interactions and how often these drugs are prescribed in nursing homes, determining that the top 10 combinations are:
1. warfarin and NSAIDs
2. warfarin and sulfa drugs
3. warfarin and macrolides
4. warfarin and quinolones
5. warfarin and phenytoin
6. ACE inhibitors and potassium supplements
7. ACE inhibitors and spironolactone
8. digoxin and amiodarone
9. digoxin and verapamil
10. theophylline and quinolones
AMDA's Web site provides more information on the list, including: generic and brand names of the drugs, methods to prevent interactions and answers to other common questions about the drug interactions.
A grant by GlaxoSmithKline supported the effort.
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