History Of Medicine Timeline
Vaccine Timeline - The Impact of New Technologies in Medicine PHILIP COHEN TALKS TO MARGARET LUI FROM CHIRON CORPORATION,CALIFORNIA, ABOUT THE HISTORY OF VACCINES AND IMMUNISATION
2004? Vaccines to dampen response of autoimmune disease enter clinical trials
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2001? Catalytic antibodies for passive immunity to cocaine start trials
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1999 Vaccine for hypercholesterolaemia enters clinical trials
1999 Vaccines to counter hay fever allergies enter clinical trials
1998 Transgenic potato vaccines shown to be immunogenic in humans
1997 Adjuvant MF59 licensed
1995 First trial for DNA vaccines for HIV
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1989 Haemophilus influenzae conjugate vaccine licensed
26 October 1977 Ali Maow Maalin in Somalia becomes last person to be infected with wild smallpox. He survives poliomyelitis approved in United States
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1960 Sabin oral vaccine for poliomylitis approved in United States
1921 Camille Calmette and Alphonse Guerin administer an attenuated bacterial vaccine against tuberculosis orally to a newborn infant
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1884 Jaime Ferran inoculated tens of thousands of people against Vibrio cholerae with a live, weakened vaccine in Spain. The effectiveness of the vaccine was later questioned
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1721 After observing variolation performed abroad, Lady Mary Wortley Montagu, wife of the British Ambassador to Turkey, has first variolation in England performed on her 3 year old daughter
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430 BC General Thucydides notes the appearance of natural immunity in victims of a plague that sweeps through Athens. "No one was ever attacked a second time," he notes in his history of the Peloponnesian wars
2003? Alphavirus vectors for HIV and hepatitis C virus enter clinical trials
20017 Attenuated toxins such as LTK63, a heat labile toxin of Escherichia coil, are used as nasal adjuvants in clinical trials
1999 Vaccines for hepatitis B and C viruses, HIV, and human papillomavirus in trials
1999 Delivery of vaccine via skin patch enters clinical trials
1998 Nasally delivered influenza vaccine completes clinical trials
1995 First results published from birdpox vector trial for HIV
1991 First trial for live oral attenuated Salmonella typhi vector vaccine
1981 Recombinant DNA hepatitis B vaccine licensed
1971 Live attenuated measles, mumps, and rubella (MMR)vaccine licensed
1955 Salk inactivated poliomyelitis vaccine proves effective
1896 Richard Pfeiffer and Almoth Wright independently prepare heat inactivated vaccine against typhoid bacilli
1885 Louis Pasteur vaccinates 9 year old Joseph Meister against rabies
1881 Louis Pasteur, Emile Roux, and Charles Chamberland publicly immunise sheep, cows, and a goat against anthrax
1790 Edward Jenner uses viruses derived from a cow to vaccinate a child against smallpox
Circa 1000 AD First records of Chinese variolation-the inoculation of a patient with material squeezed from the pustules of a sufferer of mild smallpox
COPYRIGHT 1999 British Medical Association
COPYRIGHT 2000 Gale Group
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