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History Of Medicine Timeline

Vaccine Timeline - The Impact of New Technologies in Medicine

PHILIP COHEN TALKS TO MARGARET LUI FROM CHIRON CORPORATION,CALIFORNIA, ABOUT THE HISTORY OF VACCINES AND IMMUNISATION

2004? Vaccines to dampen response of autoimmune disease enter clinical trials

24.45.00

2001? Catalytic antibodies for passive immunity to cocaine start trials

24.45.70

1999 Vaccine for hypercholesterolaemia enters clinical trials

1999 Vaccines to counter hay fever allergies enter clinical trials

1998 Transgenic potato vaccines shown to be immunogenic in humans

1997 Adjuvant MF59 licensed

1995 First trial for DNA vaccines for HIV

25.37.10

1989 Haemophilus influenzae conjugate vaccine licensed

26 October 1977 Ali Maow Maalin in Somalia becomes last person to be infected with wild smallpox. He survives poliomyelitis approved in United States

24.41.05

1960 Sabin oral vaccine for poliomylitis approved in United States

1921 Camille Calmette and Alphonse Guerin administer an attenuated bacterial vaccine against tuberculosis orally to a newborn infant

25.61.10

1884 Jaime Ferran inoculated tens of thousands of people against Vibrio cholerae with a live, weakened vaccine in Spain. The effectiveness of the vaccine was later questioned

25.76.00

1721 After observing variolation performed abroad, Lady Mary Wortley Montagu, wife of the British Ambassador to Turkey, has first variolation in England performed on her 3 year old daughter

26.05.02

430 BC General Thucydides notes the appearance of natural immunity in victims of a plague that sweeps through Athens. "No one was ever attacked a second time," he notes in his history of the Peloponnesian wars

2003? Alphavirus vectors for HIV and hepatitis C virus enter clinical trials

20017 Attenuated toxins such as LTK63, a heat labile toxin of Escherichia coil, are used as nasal adjuvants in clinical trials

1999 Vaccines for hepatitis B and C viruses, HIV, and human papillomavirus in trials

1999 Delivery of vaccine via skin patch enters clinical trials

1998 Nasally delivered influenza vaccine completes clinical trials

1995 First results published from birdpox vector trial for HIV

1991 First trial for live oral attenuated Salmonella typhi vector vaccine

1981 Recombinant DNA hepatitis B vaccine licensed

1971 Live attenuated measles, mumps, and rubella (MMR)vaccine licensed

1955 Salk inactivated poliomyelitis vaccine proves effective

1896 Richard Pfeiffer and Almoth Wright independently prepare heat inactivated vaccine against typhoid bacilli

1885 Louis Pasteur vaccinates 9 year old Joseph Meister against rabies

1881 Louis Pasteur, Emile Roux, and Charles Chamberland publicly immunise sheep, cows, and a goat against anthrax

1790 Edward Jenner uses viruses derived from a cow to vaccinate a child against smallpox

Circa 1000 AD First records of Chinese variolation-the inoculation of a patient with material squeezed from the pustules of a sufferer of mild smallpox

COPYRIGHT 1999 British Medical Association
COPYRIGHT 2000 Gale Group




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